Artemisinin 98 feem pua

Taw qhia

Artemisinin 98 feem pua ​​yog tsuas yog muab los ntawm artemisia annua.Los yog extract artemisinic acid nyob rau hauv lub siab dua cov ntsiab lus ntawm artemisia annua, thiab ces semi txo synthesis.Tam sim no, tsis muaj lwm yam tej yam ntuj tso nroj tsuag muaj artemisinin tsuas yog artemisia annua.Txawm hais tias artemisia annua yog dav faib nyob rau hauv lub ntiaj teb, cov ntsiab lus ntawm artemisol sib txawv heev nrog ntau qhov chaw tsim khoom.Raws li cov kev tshawb fawb tau los txog tam sim no, artemisinin cov ntsiab lus hauv artemisia annua tsim nyob rau hauv feem ntau cov cheeb tsam ntawm lub ntiaj teb no yog tsawg heev, tsis muaj nqi, tsuas yog nyob rau hauv lub sab hnub tuaj ntawm Chongqing. , Fujian, Guangxi thiab qee qhov chaw ntawm Hainan.Raws li kev tshawb nrhiav los ntawm lub xeev cov tuam tsev, artemisinin loj hlob nyob rau hauv wumu Roob hauv Youyang cheeb tsam ntawm Chongqing, Tuam Tshoj, yog ntawm industrial extraction nqi thoob ntiaj teb.

Artemisinin Powderis ib rab koob tsis muaj xim txo tau zoo li siv lead ua nrog lub melting point ntawm 156 157 degree. Nws yog soluble nyob rau hauv chloroform, acetone, ethyl acetate thiab benzene, soluble nyob rau hauv ethanol thiab ether, me ntsis soluble nyob rau hauv txias petroleum ether, yuav luag insoluble nyob rau hauv dej.Vim nws tshwj xeeb peroxide pawg, nws yog thermally unstable thiab yooj yim decomposed los ntawm ntub, kub thiab cov tshuaj txo qis.

Cov ntaub ntawv khoom

Muaj nuj nqi

1.Artemisinin 98 feem pua ​​tuaj yeem ua rau tib neeg lub siab qeeb

2.Nws tuaj yeem inhibit qhov contractility ntawm tib neeg myocardium

3.Bactericidal thiab bacteriostatic

4. Txhawb kev tiv thaiv

5.Natural Artemisinin tuaj yeem tswj cov kev qhia ntawm cyclin hauv cov qog hlwb

Daim ntawv thov

1. Artemisinin 98 feem pua ​​muaj lub luag haujlwm hais txog kev tswj cov kev qhia ntawm cyclin hauv cov qog nqaij hlav.In vitro thwmsim pom tau tias ib koob tshuaj artemisinin tuaj yeem ua rau apoptosis ntawm daim siab mob hlwb, qog nqaij hlav cancer mis, qog nqaij hlav qog noj ntshav thiab lwm yam qog noj ntshav, thiab inhibit Kev loj hlob ntawm cov qog nqaij hlav cancer.Nws tau pom tias artemisinin tuaj yeem tswj cov kev qhia ntawm cyclin hauv cov qog hlwb, txhim kho cov nyhuv ntawm CKIs, thiab ua rau qog cell voj voog ntes.Los yog ua rau apoptosis, inhibit qog angiogenesis thiab thiaj li tiv thaiv qhov tshwm sim. thiab kev loj hlob ntawm qog.

2. Artemisinin Malaria muaj kev ua haujlwm ntawm Inhibiting the contractility ntawm tib neeg myocardium. Artemisinin tuaj yeem cuam tshuam kev loj hlob ntawm vascular endothelial hlwb thiab vascular du leeg hlwb, uas ua lub luag haujlwm tseem ceeb hauv kev kho PAH. Artemisia Annua Extract tuaj yeem cuam tshuam cov kev ua ntawm matrix metalloproteinases thiab yog li inhibit pulmonary vascular remodeling.Artemisinin tuaj yeem inhibit qhov kev qhia ntawm PAH ntsig txog cytokines thiab ntxiv txhim kho cov tshuaj tiv thaiv vascular remodeling nyhuv ntawm artemisinin.

3. Artemisinin Extract hmoov muaj covantifungal nyhuv uasKuj tseem ua rau Artemisinin nthuav tawm qee yam tshuaj tua kab mob.Studies tau lees paub tias artemisinin thiab dej decoction muaj cov tshuaj tua kab mob muaj zog ntawm Bacillus anthracis, Staphylococcus epidermis, Catarrh thiab Diphtheria, thiab tseem muaj qee yam tshuaj tua kab mob rau tuberculosis, Pseudomonas aeruginosa, Staphylococcus aeruginosa, Staphylococcus aeruginosa thiab Staphylococcus.

4. Artemisinin Powder kuj tseem yuav txuag tau cov ntshav qab zib, raws li kev tshawb fawb hauv lub Kaum Ob Hlis 1, 2016 qhov teeb meem ntawm phau ntawv xov xwm Cell qhia tau hais tias cov kws tshawb fawb los ntawm CeMM Center for Molecular Medicine ntawm Austrian Academy of Sciences thiab lwm lub koom haum tau tshawb pom tias artemisinin quot;transformsquot; glucagon txo kev tsim cov alpha hlwb rau hauv insulin txo qis tsim cov beta hlwb. Artemisinin khi rau cov protein hu ua gephyrin, uas ua rau GABA receptor, lub ntsiab hloov rau cellular signaling. Tom qab ntawd, ntau yam tshuaj biochemical tshwm sim, ua rau tsim cov tshuaj insulin. Lwm txoj kev tshawb fawb pom tau tias hauv tus qauv nas, kev txhaj tshuaj ntawm GABA kuj tau coj mus rau kev hloov pauv ntawm alpha hlwb rau hauv beta hlwb, qhia tias ob qho tib si tshuaj tsom rau tib lub tswv yim, tab sis ntev npaum li cas cov teebmeem ntawm artemisinin yuav tsum tau kuaj ntxiv.

5. Artemisinin Extract Powder thiab nws cov derivatives muaj peev xwm inhibit T lymphocyte mitogens zoo dua ntawm cov koob tshuaj uas tsis ua rau cytotoxicity, yog li inducing proliferation ntawm nas spleen lymphocytes. Qhov kev tshawb pom no muaj txiaj ntsig zoo rau kev kho mob autoimmune kho mob los ntawm T lymphocytes. Artemisinin vinegar tau txhim kho tsis txo qis kev tiv thaiv kab mob thiab muaj peev xwm ua kom tag nrho cov kev ua si ntxiv ntawm nas cov ntshav. Dihydroartemisinin ua rau muaj kev cuam tshuam ncaj qha rau kev loj hlob ntawm B lymphocytes, yog li txo qis kev tso tawm ntawm autoantibodies los ntawm B lymphocytes, txo qis kev tiv thaiv kab mob humoral, muaj kev cuam tshuam rau kev tiv thaiv kab mob humoral thiab txo qhov tsim ntawm kev tiv thaiv kab mob.

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