Tej Chitosan

Khoom Taw qhia

Bulit chitosan yog hom tsiaj cellulose uas muaj nyob hauv crustaceans thiab arthropods. Nws qhia ntau qhov tshwj xeeb ntawm kev ua haujlwm physiological tom qab deacetylated los ntawm high-tech biological txhais tau tias. Hauv xyoo 1991, nws tau qhuas los ntawm cov khoom noj khoom haus hauv Tebchaws Europe, Tebchaws Asmeskas, Nyij Pooj thiab lwm lub tebchaws raws li" ntxiv rau cov protein, rog, carbohydrates, minerals, thiab vitamins. Nws tau ua pov thawj los ntawm kev sim tshuaj uas nws muaj ntau lub zog xws li txo cov ntshav siab, txo ntshav lipids, txo cov ntshav qab zib, ntxiv dag zog rau daim siab thiab lub raum, tswj kev ua haujlwm ntawm endocrine thiab kev tiv thaiv kab mob, txwv tsis pub muaj mob cancer ntawm tes, thiab txo cov metastasis. Yog li ntawd, qee tus neeg hu nws" qhov zoo kawg nkaus chitosan." Chitosan yog qhov tam sim no feem ntau pom tseeb. Nyiv kev kawm voj voog hais tias chitosan yuav nce rau qhov kev hloov kho mob hauv xyoo pua 21st.

Khoom Piav Qhia

CAS: 9012-76-4

EINECS: 222-311-2

Specification: 99%

Zog: Dawb hmoov

MF: （C6H11NO4） N

MW: ≤3000 Ntaj

TTesting Txujci: HPLC

Txee Lub Neej: 2 Xyoos

COA

Cov yam ntxwv ntawm Chitosan

1. Cov kab mob chitosan zoo rau them cov cationic pawg hauv qab cov kua qaub ntev, xws li cov tshuaj tiv thaiv hauv pais plab acid.

2. Cov chitosan ntau tuaj yeem nkag rau hauv tib neeg lub cev tom qab tau decomposed los ntawm enzymes lossis nqus tau ncaj qha. Chitosan tuaj yeem decomposed mus rau hauv cov tshuaj yuag tsawg hauv cov tib neeg lub cev los ntawm lysozyme, decomposing enzyme thiab lecithin. Cov kev tshawb fawb pom tau hais tias thaum chitosan yog decomposed rau hauv polymer muaj li ntawm 6 glucosamine lwg me me, nws nkag mus rau tib neeg cov ntaub so ntswg thiab nthuav tawm kev ua haujlwm ntawm lub cev, thiab nws lub cev kev tswj hwm kev ua haujlwm yog qhov tseem ceeb tshaj.

3. Loj chitosan muaj qhov txiaj ntsig zoo rau lub hlwb. Cov lysed oligoglucosamine thiab glucosamine zoo heev rau cov khoom sib txuas ntawm cov tib neeg lub hlwb-hyaluronic acid, yog li lawv muaj kev sib raug zoo thiab tsis tsim cov kev tsis lees paub rau tib neeg lub cev.

4. Loj chitosan muaj qhov muaj zog adsorption thiab chelation. Cov chitosan yaj hauv cov kua qaub yog nyob rau hauv lub xeev gel thiab muaj lub zog muaj zog adsorption. Nyob rau tib lub sijhawm, hydroxyl pawg ntawm oligoglucosamine thiab glucosamine raug cuam tshuam los ntawm ortho amino pawg los chelate nrog cov hlau ions hnyav, thiab chelation coefficient nce nrog qhov nce ntawm cov hlau atomic nyhav.

5. Bulk chitosan zoo thiab tsis muaj tshuaj lom thiab phiv. Chitosan yog ntuj cellulose, non-toxic, tsis muaj kev phiv tshuaj, thiab nws txoj kev nyab xeeb yog tib yam li cov suab thaj.

6. Ntau qhov chitosan tsis txwv rau qee yam kabmob tshwj xeeb. Nws tuaj yeem tswj tau txoj haujlwm thiab kev ua haujlwm ntawm txhua lub hlwb, ntaub so ntswg thiab kabmob hauv lub cev.

Chitosan rau mob qog noj ntshav

Bulit chitosan tuaj yeem ntxiv dag zog rau kev tiv thaiv kab mob thiab txwv tsis pub muaj mob qog noj ntshav. Chitosan muaj cov haujlwm ua haujlwm ntawm kev tswj hwm thiab txhim kho lub cev' s kev tiv thaiv kab mob, txhawb kev tsim cov tshuaj tiv thaiv, thiab txhim kho lub cev' s muaj peev xwm los tiv thaiv cov kab mob.Qhov cuam tshuam cov khoom ntawm chitin, glucosamine, hloov pauv pH ntawm lub cev ua kua thiab ua kom muaj lymphocytes los tiv thaiv kev mob kheesxaws ntawm tes metastasis.

Bulit chitosan yog siv los ua kev pab cuam nyob rau hauv kev kho mob." Chitosan" muaj cov txiaj ntsig zoo rau mob qog noj ntshav thaum ntxov. Nws tuaj yeem txhim kho cov curative zoo, txo qhov mob thiab lub neej ntev los ntawm kev koom tes nrog kev kho mob tshwj xeeb hauv nruab nrab thiab theem kawg. Nws cov anti-cancer mechanism yog:

-Bulk chitosan tuaj yeem tiv thaiv kev mob qog nqaij hlav cancer ntshav. Nrog rau mob qog noj ntshav, koj yuav poob ceeb thawj sai sai, poob phaus, ua rau neeg tsis muaj zog, thiab tsis qab los noj mov. Qhov no yog vim tias cov qog nqaij hlav cancer tso cov tshuaj lom neeg mob cancer. Cov taug lom no txo ​​cov hlau nyob hauv ntshav dej thiab ua kom ntshav khiav ceev; nws ua rau ntawm qhov chaw satiety kom poob qab, thiab ua kom nrawm rau cov roj thiab cov protein tsis sib haum hauv lub cev, ua rau lub cev poob thiab tseem cachexia. Cov neeg mob qog noj ntshav muaj qhov tsis txaus siab tom qab noj chitosan vim tias nws cov nyhuv inhibitory cuam tshuam rau cov qog nqaij hlav cancer lom.

-Bulk chitosan ua kom muaj cov lymphocytes uas tuaj yeem tua cov kabmob kheesxaws. Muaj ntau cov lymphocytes hauv lub cev (xws li NK hlwb, LAK hlwb), uas tuaj yeem ua rau lub hlwb tsis zoo thiab cov qog nqaij hlav cancer, uas yog lub cev' s ua kom lub cev tsis muaj zog. Lub luag haujlwm ntawm lymphocytes hauv kev tua cov qog nqaij hlav cancer feem ntau nyob ib puag ncig pH 7.4. Kev siv cov metabolism hauv cov kabmob kheesxaws feem ntau ua raws cov kab mob glycolysis uas muaj suab thaj, thiab cov lactic acid yog tsim thaum lub cev metabolism. Yog li, lymphocytes uas tua qog hauv acidic ib puag ncig ntawm cov kabmob kheesxaws. Lub chitosan ua rau pH ntawm lub cev dej txav mus rau sab alkali. 5. Tsim qhov chaw uas lymphocytes tua cov qog noj ntshav.

-Bulk chitosan tiv thaiv kab mob qog nqaij hlav cancer metastasis. Mob kheesxaws ntawm tes metastasis feem ntau dhau los ntawm cov hlab ntshav. Muaj ib qho kev nplaum rau ntawm cov nplais ntawm cov hlwb endothelial. Cov qog mob qog nqaij hlav tuaj yeem ua raws li qhov nplaum adhesion kom nkag mus rau cov hlab ntshav, thiab tom qab ntawd ua ke nrog cov ntshav nplaum txhawm rau txav, thiab tom qab ntawd ua ke nrog lwm qhov ntawm cov nplaum adhesion los ua cov qog ntshav. Ua cov metastasis. Chitosan muaj qhov ua kom muaj zog adsorption ntawm kev ua kom yooj yim. Kab mob khees xaws tsis tuaj yeem muaj metastasize yog tias lawv nrhiav tsis tau cov khoom ua ke.

Thov

Qhov ntau ntawm cov kev tshawb fawb txog kev siv ntau cov chitosan thiab nws cov keeb kwm yav dhau los tau qhia tias chitin thiab nws cov derivatives muaj cov yeeb yaj kiab tsim cov khoom, spinnability, anticoagulant zog, thiab txhawb cov qhov txhab zoo. Yog li no, chitin thiab nws cov khoom siv tau siv dav hauv ntau qhov chaw xws li zaub mov, biochemistry, tshuaj, tshuaj pleev ib ce txhua hnub thiab dej phwj tuaj. Kev siv lub ntsiab yog cov ntsiab raws li nram no:

-Cov ntawv thov ntawm bulk chitosan hauv kev lag luam khoom noj khoom haus. Chitosan tuaj yeem siv los ua tus sawv cev, moisturizer, qhia meej ntxiv, muab tub lim, emulsifier, txhuam thiab thickening stabilizer hauv kev lag luam khoom noj khoom haus; thiab raws li lub luag haujlwm oligosaccharide, nws tuaj yeem txo cov roj cholesterol thiab txhim kho kev tiv thaiv. Txhim kho lub cev' s muaj peev xwm tiv thaiv kab mob thiab kis kab mob, tshwj xeeb yog muaj cov nyhuv los tiv thaiv qog. Vim tias nws cov khoom muaj nuj nqis thiab cov ntawv thov muaj nuj nqis, nws tau nthuav dav siv thiab siv. Hauv kev lag luam, enzymatic los yog acid hydrolysis ntawm cw nqaij tawv los yog crab plhaub yog siv los rho chitosan.

1. Raws li tus neeg nqa khoom rau immobilized enzyme, microcrystalline chitosan yog txau rau hauv lub lye rau solidification los ntawm txau cov chitosan acetic acid kua, thiab tom qab ntawd sib cais thiab tsim kom tau zoo chitosan hais. Nws tuaj yeem siv los ua tus cab kuj rau immobilized enzymes, uas tuaj yeem raug polymerized los ntawm chitosan. Cov enzymes uas tsis muaj piam thaj ntau tuaj yeem siv cov khoom siv roj ntsha hauv lub cev xws li kev ua qab zib, kev ua cawv txiv hmab, thiab kua txiv ntoo vinegar.

2. Siv los ua cov khoom noj ntxiv, microcrystalline chitosan tuaj yeem siv los ua cov zaub mov ua kom tuab thiab ruaj khov nyob rau hauv cov khoom qab zib, txiv laum huab xeeb, tahini, cov kaus poom pob kws, cov hloov pauv butter thiab lwm yam khoom noj. Feem ntau, cov cawv txiv ntoo feem ntau ua rau dej nag tom qab tau ntev ntev. Qhov no feem ntau yog los ntawm kev tsim cov macromolecular txoj kev nyuaj ntawm cov hlau ions thiab phenolic acids xws li tannins. Cov kua qaub tau kho nrog chitin thiab chitosan tsis ua sai sai tom qab ib xyoos cia. Thaum tsim cov kua ntses, ntxiv rau qhov tsim nyog ntawm chitosan tuaj yeem tshem tawm cov protein thiab tiv thaiv nag lossis daus. Ntxiv me me ntawm chitosan rau cov kua ntses yog tuaj yeem txo cov ntsev kom tsawg, thiab cov khoom yuav tsis puas ntsoog tom qab kev khaws cia ntev.

3. Raws li cov zaub mov ntim ntim zaj duab xis, chitosan, hmoov txhuv nplej siab thiab dej tau sib xyaw ua ke los ua ib zaj duab xis, thiab tom qab ntawd tau qhuav nrog lye los ua chitosan-hmoov txhuv nplej siab cov zaub mov ntim ntim, uas yog non-toxic thiab edible, Roj tsis kam, insoluble hauv dej txias thiab dej kub, lub zog loj tensile, tuaj yeem siv rau pob cov khoom ntim, cov khoom siv ib nrab thiab khoom noj muaj kua, cov zaj duab xis tuaj yeem ua tiav biodegrade, yog li tsis muaj cov pa phem ib puag ncig.

4. Siv rau kev tiv thaiv khoom noj thiab txuag. Chitosan tuaj yeem siv los khaws cov khoom noj tshiab ntawm cov zaub, nqaij cov khoom lag luam, cov nqaij nruab deg, cov hmoov txhuv nplej siab, cov khoom ua kua, thiab cov qe, mis thiab kua zaub.

-Cov ntawv thov ntawm bulk chitosan hauv tshuaj txhua hnub. Chitosan yog non-toxic, mov, thiab muaj cov kab mob antibacterial. Thaum tsim hauv cov tshuaj pleev ib ce, nws tuaj yeem txhim kho zaj duab xis-ua cov khoom ntawm cov khoom, muaj cov tshuaj tua kab mob thiab ua kom lub zog, thiab tsis ua rau muaj kev ua xua. Piv txwv li, los ntawm kev qhia tawm hydroxypropyl ammonium chloride pawg rau chitosan molecule, tau txais chitosan hydroxypropyl trimethyl ammonium chloride tuaj yeem txhim kho lub peev xwm ntawm chitosan, txhim kho nws lub noo noo nqus thiab moisturizing efficiency, thiab dhau los ua cov khoom muaj txiaj ntsig, ib qho khoom siv zoo nkauj noo nrog kev ua haujlwm zoo. Ntau yam tshuaj zawv plaub hau thiab cov khoom tu plaub hau ua los ntawm kev ntxiv rau chitosan muaj qhov cuam tshuam ntawm kev sib txuas yooj yim, plaub hau npliag, plump tes zoo nkauj thiab xim plaub hau xim. Nws yog qhov zoo dua rau cov plaub hau nyias nyias uas yooj yim kom tawg thiab phua xaus. Pua pua ntawm cov tshuaj pleev ib ce txhua hnub uas muaj chitosan tau muag hauv Europe, Tebchaws Asmeskas, Nyij Pooj thiab lwm lub tebchaws thiab thaj chaw.

-Txoj kev cuam tshuam ntawm Bulk Chitosan hauv Kev lag luam Kev Siv Tshuaj Chitosan yog siv rau hauv cov kws tshaj lij tshuaj, kev faib tawm, ua kom tuab, thiab lwm yam.

1. Cov khoom thauj khoom, siv cov chitosan ua cov tshuaj xa tuaj yeem ua kom ruaj khov cov tshuaj hauv cov tshuaj, txhawb kev nqus tshuaj, ncua lossis tswj cov tshuaj cais tawm ntawm cov tshuaj, pab cov tshuaj mus txog lub hauv paus hloov, thiab tiv cov kua qaub thiab mob rau, thiab tiv thaiv cov yeeb tshuaj los ntawm kev ua kom lub plab.

2. Cov khoom siv ua zaj duab xis, chitosan tuaj yeem siv cov khoom siv los ua cov ntaub tsoos tsho, los npaj cov zaj duab xis, tsoos suav tshuaj kho mob thiab lwm yam. Qhov txheeb ze molecular yuag muaj cov txiaj ntsig zoo ntawm kev tsim zaj duab xis thiab cov khoom siv yeeb yaj kiab. Feem ntau, qis dua qhov phaus molecular, qis qis lub zog tensile ntawm zaj duab xis thiab muaj zog permeability. Tus neeg saib xyuas cov kab txuas uas tsim nyog tuaj yeem xaiv los txhim kho lub zog ntawm zaj duab xis thiab hloov cov khoom sib txawv ntawm cov yeeb yaj kiab.

3. Threader Chitosan siv los ua cov thickener, vim tias cov concentration nce ntxiv, viscosity ntawm kev daws nce; thaum cov tshuaj qib siab dua, qhov viscosity ntawm cov tshuaj mloog tau qhia thixotropy. Thaum qhov kub nce, nws cov viscosity tsawg zuj zus, thiab txoj cai yog ua tiav nrog cov kev cai lij choj ntws ntawm cov khoom siv dav dav polymer concentrated kev daws teeb meem.

4. Lwm yam kev siv Chitosan tuaj yeem siv los ua cov ntsiav tshuaj ntim khoom noj thiab ua kom zoo nkauj. Chitosan muaj biocompatibility zoo thiab biodegradability. Qhov khoom puas tsuaj tuaj yeem nqus tau los ntawm lub cev yam tsis muaj kev txuam nrog hauv lub cev, tsis muaj tshuaj tiv thaiv kab mob, thiab tuaj yeem ua rau hauv kev nqus phais sutures

-Qhov kev thov ntawm ntau chitosan hauv kev lag luam teeb pom kev zoo, siv solubility thiab zaj duab xis-tsim cov khoom ntawm chitosan, thiab kev sib nrig sib hloov ntawm cov tshuaj qauv ntawm chitosan thiab chitin, siv acetic anhydride raws li kev hloov pauv ntawm chitosan-chitin Tus neeg sawv cev los ua chitin -type thiab tiag tiag formaldehyde-dawb tshiab npuag xov tus neeg sawv cev (nws tsis tsuas yog khaws qhov zoo ntawm chitin ntuj polymer, tab sis kuj xyuas kom meej tias tus neeg sawv cev thiab ua tiav cov txheej txheem tsis muaj tshuaj lom thiab tsis muaj mob). Cov chitosan gel npaj nrog formaldehyde thiab acetic acid ua tus neeg sawv cev sib txuas thiab chitosan raws li lub hauv paus yog tsis yog soluble hauv dej, dilute acid thiab alkali cov kev daws teeb meem, tsis yog nyob rau hauv cov organic solvents, thiab muaj lub zog zoo txhua yam thiab tshuaj lom neeg. Kev ua tau zoo yav tom ntej xws li kev ruaj khov.

-Cov ntawv thov ntawm chitosan ntau hauv kev tiv thaiv ib puag ncig. Chitosan tuaj yeem cuam tshuam nrog glutaraldehyde. Kev hloov pauv ion resin-chitosan hla sib xyaw membrane yog npaj los ntawm cov txheej txheem casting. Cov peev xwm tuaj yeem adsorb hlau ions thiab tuaj yeem siv rau kev kho dej khib nyiab kev lag luam. Ua thiab rho tawm ntawm cov hlau hnyav. Chitosan tuaj yeem tsim cov chelates ruaj khov dhau ntawm cov amino pawg, hydroxyl pawg thiab hlau ions Hg {{3}}, Ni2+, Pb2+, Cd2+, Mg2+, Zn2+Cu2+, Fe3+, yog li nws tuaj yeem siv dav hauv rov qab los ntawm cov khoom muaj nqis thiab kev kho cov dej khib nyiab. thiab lwm yam kev siv ntawm chitosan los npaj cov viscosity soluble chitosan, cov khoom lag luam tawm tau muaj cov viscosity siab thiab cov khoom zoo. Nws yog siv nyob rau hauv kev kho sludge kev kho mob nrog cov teebmeem zoo. Tsis tas li ntawd, vim tias nws yog non-toxic thiab biodegradable, nws yog siv hauv cov dej khib nyiab kho thiab hlau tshem tawm. , Yuav tsis ua rau cov pa phem ntxiv, yog li nws yog kev cog lus ua polymer flocculant thiab hlau chelating tus neeg sawv cev.